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Copy of a Letter from Ar Ms/hop LAUD
To the Warden and Fellows of AllSouls Coll. Oxford.
JL good scholar, Mr. Osborn being to give over his sellowship was with me at Lambeth, and, I thank him, freely proffer'd me the nomination of a scholar to succeed in his place; now having seriously deliberated with myself touching this business, and being willing to recommend such an one to you, as you might thank me for, I am resolved to pitch upon Mr. Jeremiah Taylour of whose abilitys and sufHciencys every ways I have receiv'd very good assurance. And I do hereby heartily pray you to give him all furtherance by yourself and the sellows at the next election, not doubting but that he will approve himself a worthy and learned member of your society. And tho' he has had his breeding for the most part in the other university, yet I hope that shall be no prejudice to him, in regard that he is incorporated into Oxford (ut fit eodem ordine, gradu, &c.) and admitted into University College. Neither can I learn that there is any thing in your local statutes against it; I doubt not but you will use him with so fair respects, as befits a man of his rank and learning, for which I lhall give you thanks. So I leave him to your kindness, and rest
Salutem in Chrijro,
behalf of an honest man, and a
Your loving friend
Lambeth-House, October 23. 1635.
An extraSt of a Thesis read before Mr. Haller,
In October 1749. By Mr. F. G. Z I N N.
AFTER having adjusted the trochart to the fore part of the head, of a middle siz'd dog, over the longitudinal sinus, I plunged the instrument through the mass of the brain, in such a manner, that it was fixed strongly in the bone of the basis of the skull. After the stroke was given, the dog seeu'd as unaffected, as if nothing at all had happen'd; and continued brisk and sensible, to every thing that was done to exasperate him ; he heid up his head and look'd about him, and there was nothing particular but a little slaver, which sell from his mouth. Some time after he sell fast asleep, and I endeavour'd to rouze him, by making a noise, to no purpose; for he immediately slept "again: I then perceived that the muscles of the right side were struck with the palsy. I left him in this condition, at eleven o'clock. Returning at four, I still found him in the fame condition: but the desire I had to change the scene, caused me to withdraw the instrument. All of a sudden the face of affairs was changed: the dog began to groan, to whine and vomit: the muscles on the right side continued quite paralytick, without motion or feeling: thcsleepiness was now more strong, for we could indeed wake him, by strong irritation,but then he was more stupid, and sell asleep immediately again: at the same time his pulse was severish: I return'd to see the dog at seven, and found no alteration, but the next day he died. I immediately open'd the skull, and found the longitudinal sinus had been penetrated. The instrument, after wounding the anterior part of the corpus callosum, past towards the hind part, and a litle to the left, thro' the left ventricle, and thro' the left corpora slriata, as far as the basis of the skull, in the bone of which the instrument was fixed. EXPE
EXPERIMENT II. I thrust the fame instrument through the head of a pretty large clog, a little farther back, over the longitudinal sinus, and I left it in the wound. The dog, wounded as he was, was so lively as to listen to the barking of another dog in the neigbourhood. Returning the next day, at one in the afternoon, I found him fase and found, brisk and in no wise apoplectick; and I even perceiv'd that he had struggled very much, in order to get loose. This was on Sunday, wherefore considering that his howling might incommode the neighbourhood, he was immediately killed. After opening the brain, I found the instrument had pass'd through the middle of the corpus callosum, and had penetrated the thalatnus of the optick nerves, in the place where they meet in the anterior and superior ventricles.
EXPERIMEN, T III.
Being afraid that the apoplexy, caused by the effusion of the blood of the sinus, should hurt the experiment, I again thrust the instrument into the right side of the head of a dog, from the right to the left. The dog lived twenty two hours, constantly lively and brisk, without being paralytick, in any part of the body, except in the last hours of his lise, when the heat and pain had made him feeble: I perceived he might have lived some days longer, but being impatient, I hanged him. Then opening his head, I perceived the instrument, after having past through the middle of the corpus callosum, was fixed in the bone of the skull, on the left of the union of the optick nerves, or at the basis of the skull.
EXPERIMENT IV. At seven in the evening, I thrust the fame instrument into tljie head of a young dog, from the right to the left. At first he seem'd a little stunn'd, but came to himself, some hours afterwards, and the neighbours heard him bark all the night. The next day I found him indeed paralytick
on on one side, but more brisk and lively than the evening before. But being obliged to go a journey, I killed him at noon; and opening the cavities of the breast, by a large wound on each side, he continued to live a quarter of an hour longer. The next day I open'd the skull, and found the corpus callosum had been penetrated, ae well as the thala* tnus of the optick nerves.
Being curious to know what would happen, if the corpus tallofitm was wounded twice, I thrust the instrument from the right to the left, and then from the left to the right. After the first stroke, I unloosed the dog, who began to walk as if nothing had ailed him; nor did he seem to be more in pain after the second stroke than the first. Iwent to see him the next day, and found him more seeble, but with all his senses and motions. Willing to make other experiments on this animal, I thrust the instrument thro' the nape of the neck, into the medulla spinalis of the back, between the first vertebra and the last of the head. This wound caused a great effusion of blood: he lived another half hour, in a very languishing condition, it must be owned, but with some remains of motion and senfation. On opening the skull, I found the corpus callosum was penetrated in two places, in such a manner that almost all the anterior part was lacerated. The stroke from the left to the right was turned a little backward, and had passed thro' the pes hippocampi of the right side; the other stroke from the right to the left had passed through the left thalamus of the optick nerves, and both had penetrated as far as the skull. There was a great deal of blood spilt, in the three anterior ventricles. I found the third stroke had passed through the middle of the medulla spinalis.
After having divided the skull of a living dog, but apoplectick on account of the blood which was shed in the brain, with a faw, I cut away the brain by slices, as far as the corpus callosum, then slit the corpus callosum, and open'd the ventricles. The creature, who had been quiet while the teeth of the faw had lacerated the dura mater, began to make a noise and to struggle when the medulla was disturb'd. After having taken out the medullaoblongata, I then took out all the brain. Immediately the members began to tremble, and the motion of the heart, attended with a deep respiration, continued for some minutes. I likewise took out the cerebellum, and thrust a probe into the medulla spinalis of the back; hereupon the members sell into convulsions, and the deeper I thrust the point, the more the hind parts were in agitation.
A pigeon being depriv'd of its brain, but having the cerebellum intire, cou'd stand upon its legs, and swallow the food which had been put into its bill.
I observed in all these experiments, that the dogs discover' d signs of extreme pain, by crying and howling, while the instrument past through the medulla of the brain.
EXPERIMENT VHL Another day, I thrust the instrument into the head of a dog of middle size, through the inserior part of the right side, of the hind bone, in almost an horizontal direction, 'till it remained fixed in the opposite bone. The dog was at sirst a little stunned, but came to himself by little andlittle, with great howling. This was done at six in the evening. Returning to see him the next day, at one in the afternoon, I found him brisk and lively, and the neighbours told me, that he had bark'd very much all the night. When I perceiv'd this wound had not much affected him, I withdrew the instrument, and plung'd it a little higher, through the middle of the bone of the hind part of the head. At this stroke he sell down apoplectick. When I return'd the next day, I found him dead. I open'd the sltuU, took out the brain,